'
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
6.3
USERS' SCORE
Very Good
Based on 2 Reviews
8.8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D (as D3 Cholecalciferol)
125 mcg (5,000 IU)
625%

Top Medical Research Studies

8
Vitamin D and breast cancer link
Umbrella Review on the Relationship Between Vitamin D Intake and Cancer.
Directly addresses breast cancer benefits
We examined the relationship between vitamin D intake and breast cancer, delving into how this vitamin may play a role in prevention and management. The findings suggest that vitamin D may have a protective effect, potentially lowering the risk of developing breast cancer.

While we found a notable connection, it’s important to recognize that most of the existing evidence comes from observational studies. This means we can identify associations but cannot definitively say that vitamin D causes these effects.

Additionally, there are several complexities in studying vitamin D, such as varying metabolism and differences in study designs, which make drawing firm conclusions challenging.

Although the research provides intriguing insights, more rigorous studies are necessary to truly clarify how vitamin D could be integrated into breast cancer care moving forward.
Read More
8
Vitamin D impacts breast cancer outcomes
Impact of Vitamin D Levels on Progression-Free Survival and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Systematic Review and Meta-Analysis.
Highly relevant to breast cancer research
We explored how vitamin D (VD) levels might impact breast cancer (BC) patients undergoing neoadjuvant chemotherapy (NACT). The study reviewed data from six different research projects involving patients who had confirmed diagnoses of BC and had their vitamin D levels measured before starting chemotherapy.

Our analysis revealed some intriguing findings. Specifically, maintaining adequate vitamin D levels appeared to lower the chances of not responding to neoadjuvant chemotherapy by 22%. Additionally, those with sufficient vitamin D experienced a 35% reduced risk of disease progression compared to those with low or deficient levels. This suggests that vitamin D might play a beneficial role in improving treatment outcomes for breast cancer patients.

Overall, these results underscore the importance of keeping vitamin D levels within a healthy range during cancer treatment. They encourage us to delve deeper into how vitamin D influences cancer biology and its potential as a supportive therapy in breast cancer management.
Read More
5
Vitamin D's impact on muscle strength
Low Serum Vitamin D Levels Are Associated with Reduced Muscle Strength in Women with Breast Cancer.
Highly relevant breast cancer study
We explored the connection between vitamin D levels and muscle strength in women with breast cancer. This research involved adult women who had been diagnosed with breast cancer within the last 12 months, ensuring that none had metastases or recurrences. Our focus was on understanding how inadequate vitamin D might relate to reduced muscle strength in this specific group.

We discovered that a significant portion of the participants, around 70%, had insufficient levels of vitamin D. This deficiency was notably linked to lower muscle strength, as indicated by the Handgrip Strength test. Specifically, the findings showed that women with insufficient vitamin D were more likely to fall into the lower muscle strength categories.

The study sheds light on the importance of monitoring vitamin D levels in women battling breast cancer. Given the link between low vitamin D and weaker muscle strength, addressing this deficiency might offer a new avenue for improving overall health and vitality in these patients.
Read More

Most Useful Reviews

8.8
Immune function support
I prefer Jarrow Vitamin D3 for its effects on immune function, significantly enhancing my wellbeing. It's also suggested that maintaining vitamin D sufficiency may reduce the long-term risk of developing breast cancer and certain infections, including COVID-19.
Read More
8.8
Cell differentiation
Vitamin D promotes cell differentiation, helping to prevent immature cells from developing into cancer cells. It also induces 'apoptosis', allowing old or diseased cells to die naturally. Notably, blood vitamin D levels are closely linked to breast cancer, colon cancer, and prostate cancer.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
6.3
8
Vitamin D and breast cancer link
Umbrella Review on the Relationship Between Vitamin D Intake and Cancer.
Directly addresses breast cancer benefits
We examined the relationship between vitamin D intake and breast cancer, delving into how this vitamin may play a role in prevention and management. The findings suggest that vitamin D may have a protective effect, potentially lowering the risk of developing breast cancer.

While we found a notable connection, it’s important to recognize that most of the existing evidence comes from observational studies. This means we can identify associations but cannot definitively say that vitamin D causes these effects.

Additionally, there are several complexities in studying vitamin D, such as varying metabolism and differences in study designs, which make drawing firm conclusions challenging.

Although the research provides intriguing insights, more rigorous studies are necessary to truly clarify how vitamin D could be integrated into breast cancer care moving forward.
Read More
8
Vitamin D's potential in breast cancer
FAP-targeting biomimetic nanosystem to restore the activated cancer-associated fibroblasts to quiescent state for breast cancer radiotherapy.
Study explores vitamin D effects
We explored the role of vitamin D, specifically calcipotriol, in targeting cancer-associated fibroblasts (CAFs) within the breast cancer microenvironment. CAFs are crucial players in tumor behavior, influencing growth, recurrence, and treatment resistance.

Our study introduced a cutting-edge nanosystem designed to deliver calcipotriol directly to activated CAFs. This approach aimed to transition these cells back to a quiescent state, curtailing their contributions to tumor progression and boosting immune responses against tumors.

When we tested this strategy, we discovered that calcipotriol effectively activated the vitamin D receptors on CAFs. This activation encouraged a shift away from a pro-tumor environment. Moreover, by combining our treatment with radiotherapy, we significantly enhanced the sensitivity of tumors to radiation while increasing the presence of cytotoxic T cells in the tumor area.

Ultimately, the findings suggest that this vitamin D treatment, packaged in a biomimetic nanosystem, has promising potential for improving breast cancer therapies. It not only assists in modifying the behavior of supportive cells in tumors but also boosts the body's immune response.
Read More
8
Vitamin D impacts breast cancer outcomes
Impact of Vitamin D Levels on Progression-Free Survival and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Systematic Review and Meta-Analysis.
Highly relevant to breast cancer research
We explored how vitamin D (VD) levels might impact breast cancer (BC) patients undergoing neoadjuvant chemotherapy (NACT). The study reviewed data from six different research projects involving patients who had confirmed diagnoses of BC and had their vitamin D levels measured before starting chemotherapy.

Our analysis revealed some intriguing findings. Specifically, maintaining adequate vitamin D levels appeared to lower the chances of not responding to neoadjuvant chemotherapy by 22%. Additionally, those with sufficient vitamin D experienced a 35% reduced risk of disease progression compared to those with low or deficient levels. This suggests that vitamin D might play a beneficial role in improving treatment outcomes for breast cancer patients.

Overall, these results underscore the importance of keeping vitamin D levels within a healthy range during cancer treatment. They encourage us to delve deeper into how vitamin D influences cancer biology and its potential as a supportive therapy in breast cancer management.
Read More
8
Vitamin D aids breast cancer nutrition
The Effects of Omega-3 Fatty Acids and Vitamin D Supplementation on the Nutritional Status of Women with Breast Cancer in Palestine: An Open-Label Randomized Controlled Trial.
Mixed effects with omega-3
We focused on the effect of vitamin D treatment, alongside omega-3 fatty acids, on the nutritional status of women newly diagnosed with breast cancer in Palestine. In this study, 88 participants were divided into four groups: one receiving omega-3 supplements, another getting vitamin D, a third combining both, and a control group without active treatment.

Over a nine-week period, we provided patients with daily omega-3 capsules and weekly vitamin D tablets. After this intervention, we measured the participants' nutritional status using various tools, including the Patient-Generated Subjective Global Assessment (PG-SGA) which helped us gauge changes in their wellbeing.

Our results showed that women who received the combined omega-3 and vitamin D supplementation experienced improvements in their nutritional status. This was evident through better PG-SGA scores, favorable changes in anthropometric measurements, and enhanced blood albumin levels, along with increases in dietary energy and protein intake.

Overall, this indicates that introducing vitamin D and omega-3 fatty acids can support nutritional health during breast cancer treatments, yet the specific effects of vitamin D alone remain intertwined with those of omega-3 supplementation.
Read More
8
Vitamin D improves life quality
The effects of Omega-3 fatty acids and vitamin D supplementation on the quality of life and blood inflammation markers in newly diagnosed breast cancer women: An open-labelled randomised controlled trial.
Moderate relevance due to overlap
We conducted a study to explore the effects of vitamin D and omega-3 fatty acids on the quality of life of women newly diagnosed with breast cancer. Our research involved 88 participants who were randomly assigned to one of four groups. Each group received either omega-3 supplements, vitamin D, a combination of both, or no supplementation at all for a period of nine weeks.

Throughout the study, we assessed the women's quality of life using specific questionnaires and measured markers of inflammation in their blood. Our main aim was to see if vitamin D could play a beneficial role alongside omega-3 in improving health outcomes during their chemotherapy treatment.

The results showed that those taking vitamin D, whether alone or with omega-3, reported a significant improvement in their quality of life as well as reductions in inflammation markers. This indicates that vitamin D may have a positive impact on the overall health status and well-being of women facing the challenges of breast cancer treatment.
Read More

User Reviews

USERS' SCORE
Very Good
Based on 2 Reviews
8.8
8.8
Cell differentiation
Vitamin D promotes cell differentiation, helping to prevent immature cells from developing into cancer cells. It also induces 'apoptosis', allowing old or diseased cells to die naturally. Notably, blood vitamin D levels are closely linked to breast cancer, colon cancer, and prostate cancer.
Read More
8.8
Immune function support
I prefer Jarrow Vitamin D3 for its effects on immune function, significantly enhancing my wellbeing. It's also suggested that maintaining vitamin D sufficiency may reduce the long-term risk of developing breast cancer and certain infections, including COVID-19.
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